Human anti-Alpha Hemolysin (Hla) mAb (327)

产品号:S200-001

产品详情:The staphylococcal alpha-toxin (Hla) is a major virulence factor contributing to Staphylococcus aureus pathogenesis. Hla is encoded by the hly gene and produces a 293-residue protein monomer capable of forming beta-barrel pores. Seven monomers come together on the host cell membrane to form a 14-angstrom pore that leads to apoptosis. The alpha toxin plays a large role in the apoptosis of immune cells such as T-cells, monocytes, and peripheral blood lymphocytes¹. Eliteimmune’s anti-Hla mAb 327 is able to neutralize Hla in toxin neutralization assays (TNA) and targets a linear epitope on Hla, making it a useful research tool for western blots and ELISAs.

产品类别: Monoclonal Antibody

病毒株: Staphylococcus aureus

相似产品名称: α-hemolysin, Hla, alpha toxin, alpha-toxin, alpha-hemolysin

表达宿主: CHO

蛋白标签: None

纯度: > 95% by SDS-PAGE

应用: ELISA, Western Blot, SDS-PAGE, toxin neutralization assays (TNA). Specific conditions should be optimized by end user.

制剂: PBS

存储条件: 4°C for immediate use, -80°C for long-term storage. Avoid repeated freeze thaw cycles.

运输条件: Dry Ice

目的用途: For research use only. Not intended for human, therapeutic, or diagnostic use. Buyer may not modify, sell, or transfer product for commercial use without written permission from Eliteimmune.

For customers located in the United States and EU, please purchase here.

Recommended Dilutions:

ELISA: Assay-dependent dilution. The antibody can be used for capture of Hla in an indirect ELISA assay and Western blot detection. 

WB: Suggested use dilution of 0.50 µg/mL

Neutralization: Assay-dependent dilution

Cross Reactivity:  This antibody does not appear to cross react with S. aureus antigens LukF, LukS, SEA, or SEB, at the tested concentrations.

Alternative Names:

α-hemolysin, Hla, alpha toxin, alpha-toxin, alpha-hemolysin